Cancer Cell Line Encyclopedia Rna Seq

The ccle cancer cell line encyclopedia project is a collaboration between the broad institute and the novartis institutes for biomedical research and its genomics institute of the novartis research foundation to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer.

Cancer cell line encyclopedia rna seq. May 15 2019. 2020 the broad institute of mit harvard. Ccle cancer cell line encyclopedia cclf cancer cell line factory drug repurposing hub prism. The original cancer cell line encyclopedia ccle is expanded with deeper characterization of over 1 000 cell lines including genomic transcriptomic and proteomic data and integration with.

B violin plot shows number of circrnas identified in cancer lineages with at least 10 cancer cell lines. Additionally wes data for 326 cell lines available from gdc were also obtained and variants were identified. You may have been redirected here from the broad cancer program resource gateway which is no longer active. Please see below for a partial list of resources or refer to the list of cancer related data software and tools.

Cell lines were profiled in their baseline unperturbed state. Place your mouse cursor over the project title. Access the ccle public project by selecting cancer cell line encyclopedia ccle from public projects in the top navigation bar n2. Project information box is displayed n3.

Rna seq of 39 human cancer cell lines that are in the nci 60 set from the cancer cell line encyclopedia. A combination of four computational pipelines to identify circrnas in cancer cell line encyclopedia ccle rna seq data. Rna seq data for 934 cell lines available from the nci gdc legacy portal https portal gdc cancer gov were downloaded and bam files were processed to call variants using an in house pipeline described earlier in the methods section. Rna seq of 934 human cancer cell lines from the cancer cell line encyclopedia rna seq mrna baseline.

C tissue specific circrna profile across cancer lineages.